IUBMB Enzyme Nomenclature


Accepted name: arylformamidase

Reaction: N-formyl-L-kynurenine + H2O = formate + L-kynurenine

For diagram of reaction click here.

Other name(s): kynurenine formamidase; formylase; formylkynureninase; formylkynurenine formamidase; formamidase I; formamidase II

Systematic name: aryl-formylamine amidohydrolase

Comments: Also acts on other aromatic formylamines.

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, PDB, CAS registry number: 156229-75-3


1. Hayaishi, O. and Stanier, R.Y. The bacterial oxidation of tryptophan. III. Enzymatic activities of cell-free extracts from bacteria employing the aromatic pathway. J. Bacteriol. 62 (1951) 691-709.

2. Jakoby, W.B. Kynurenine formamidase from Neurospora. J. Biol. Chem. 207 (1954) 657-663.

3. Mehler, A.H. and Knox, W.E. The conversion of tryptophan to kynurenine in liver. II. The enzymatic hydrolysis of formylkynurenine. J. Biol. Chem. 187 (1950) 431-438.

[EC created 1961]

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