IUBMB Enzyme Nomenclature


Accepted name: L-lysine-lactamase

Reaction: (S)-2-aminohexano-6-lactam + H2O = L-lysine

Glossary: (S)-2-aminohexano-6-lactam = L-lysine 1,6-lactam

Other name(s): L-α-aminocaprolactam hydrolase; L-lysinamidase; L-lysine-1,6-lactam lactamhydrolase

Systematic name: (S)-2-aminohexano-6-lactam lactamhydrolase

Comments: Also hydrolyses L-lysinamide.

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, CAS registry number: 52652-61-6


1. Fukumura, T., Talbot, G., Misono, H., Teremura, Y., Kato, K. and Soda, K. Purification and properties of a novel enzyme, L-α-amino-ε-caprolactamase from Cryptococcus laurentii. FEBS Lett. 89 (1978) 298-300. [PMID: 26602]

2. Shvyadas, V.K., Galaev, I.Yu. and Kozlova, E.V. Preparation and characterization of L-α-aminocaprolactam hydrolase from cells of Cryptococcus laurentii. Biochemistry (Moscow) 49 (1984) 1268-1273.

[EC created 1981, modified 1989]

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