IUBMB Enzyme Nomenclature


Accepted name: arginase

Reaction: L-arginine + H2O = L-ornithine + urea

For diagram click here.

Other name(s): arginine amidinase; canavanase; L-arginase; arginine transamidinase

Systematic name: L-arginine amidinohydrolase

Comments: Also hydrolyses α-N-substituted L-arginines and canavanine.

Links to other databases: BRENDA, EXPASY, GTD, KEGG, Metacyc, PDB, CAS registry number: 9000-96-8


1. Bach, S.J. and Killip, J.D. Studies on the purification and the kinetic properties of arginase from beef, sheep and horse liver.Biochim. Biophys. Acta 47 (1961) 336-343.

2. Cabello, J., Basilio, C. and Prajoux, V. Kinetic properties of erythrocyte- and liver arginase. Biochim. Biophys. Acta 48 (1961) 148-152.

3. Dumitru, I.F. Study of L-arginine amidinohydrolase from vegetable origin. Purification, crystallization and molecular weight. Acta Vitamin. Enzymol. 27 (1973) 207-210.

4. Greenberg, D.M. Arginase, in Boyer, P.D., Lardy, H. and Myrbäck, K. (Eds.), The Enzymes, 2nd edn., vol. 4, Academic Press, New York, 1960, pp. 257-267.

5. Greenberg, D.M., Bagot, A.E. and Roholt, O.A. Liver arginase. III. Properties of highly purified arginase. Arch. Biochem. Biophys. 62 (1956) 446-453.

[EC created 1961]

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