IUBMB Enzyme Nomenclature


Accepted name: protein-arginine deiminase

Reaction: protein L-arginine + H2O = protein L-citrulline + NH3

Other name(s): peptidylarginine deiminase; PAD

Systematic name: protein-L-arginine iminohydrolase

Comments: Also acts on N-acyl-L-arginine and, more slowly, on L-arginine esters.

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, PDB, CAS registry number: 75536-80-0


1. Fujisaki, M. and Sugawara, K. Properties of peptidylarginine deiminase from the epidermis of newborn rats. J. Biochem. (Tokyo) 89 (1981) 257-263. [PMID: 7217033]

[EC created 1983]

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