Reaction: protein L-arginine + H2O = protein L-citrulline + NH3
Other name(s): peptidylarginine deiminase; PAD
Systematic name: protein-L-arginine iminohydrolase
Comments: Also acts on N-acyl-L-arginine and, more slowly, on L-arginine esters.
Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, PDB, CAS registry number: 75536-80-0
References:
1. Fujisaki, M. and Sugawara, K. Properties of peptidylarginine deiminase from the epidermis of newborn rats. J. Biochem. (Tokyo) 89 (1981) 257-263. [PMID: 7217033]