IUBMB Enzyme Nomenclature


Accepted name: guanidinopropionase

Reaction: 3-guanidinopropanoate + H2O = β-alanine + urea

Other name(s): GPase; GPH

Systematic name: 3-guanidinopropanoate amidinopropionase

Comments: Requires Mn2+. Also acts, more slowly, on taurocyamine and 4-guanidinobutanoate.

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, PDB, CAS registry number: 68821-77-2


1. Yorifuji, T., Sugai, I., Matsumoto, H. and Tabuchi, A. Characterization of 3-guanidinopropionate amidinohydrolase from Pseudomonas aeruginosa and a comparative study with 4- guanidinobutyrate amidinohydrolase from another Pseudomonas. Agric. Biol. Chem. 46 (1982) 1361-1363.

[EC created 1989]

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