IUBMB Enzyme Nomenclature


Accepted name: cytosine deaminase

Reaction: cytosine + H2O = uracil + NH3

Other name(s): isocytosine deaminase

Systematic name: cytosine aminohydrolase

Comments: Also acts on 5-methylcytosine.

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, PDB, CAS registry number: 9025-05-2


1. Cohen, S.S. and Barner, H.D. The conversion of 5-methyldeoxycytidine to thymidine in vitro and in vivo. J. Biol. Chem. 226 (1957) 631-642.

2. Kream, J. and Chargaff, E. On the cytosine deaminase of yeast. J. Am. Chem. Soc. 74 (1952) 5157-5160.

[EC created 1961]

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