IUBMB Enzyme Nomenclature


Accepted name: pterin deaminase

Reaction: a 2-amino-4-hydroxypteridine + H2O = a 2,4-dihydroxypteridine + NH3

Other name(s): acrasinase

Systematic name: 2-amino-4-hydroxypteridine aminohydrolase

Comments: The animal enzyme is specific for pterin, isoxanthopterin and tetrahydropterin.

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, CAS registry number: 9025-04-1


1. Levenberg, B. and Hayaishi, O. A bacterial pterin deaminase. J. Biol. Chem. 234 (1959) 955-961.

2. Rembold, H. and Simmersbach, F. Catabolism of pteridine cofactors. II. A specific pterin deaminase in rat liver. Biochim. Biophys. Acta 184 (1969) 589-596. [PMID: 5821022]

[EC created 1965]

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