Reaction: a 2-amino-4-hydroxypteridine + H2O = a 2,4-dihydroxypteridine + NH3
Other name(s): acrasinase
Systematic name: 2-amino-4-hydroxypteridine aminohydrolase
Comments: The animal enzyme is specific for pterin, isoxanthopterin and tetrahydropterin.
Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, CAS registry number: 9025-04-1
References:
1. Levenberg, B. and Hayaishi, O. A bacterial pterin deaminase. J. Biol. Chem. 234 (1959) 955-961.
2. Rembold, H. and Simmersbach, F. Catabolism of pteridine cofactors. II. A specific pterin deaminase in rat liver. Biochim. Biophys. Acta 184 (1969) 589-596. [PMID: 5821022]