Reaction: guanine + H2O = xanthine + NH3
Other name(s): guanase; guanine aminase; GAH
Systematic name: guanine aminohydrolase
Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, PDB, CAS registry number: 9033-16-3
References:
1. Hitchings, G.H. and Falco, E.A. The identification of guanine in extracts of Girella nigricans. The specificity of guanase. Proc. Natl. Acad. Sci. USA 30 (1944) 294-297.
2. Kalckar, H.M. Differential spectrophotometry of purine compounds by means of specific enzymes. III. Studies of the enzymes of purine metabolism. J. Biol. Chem. 167 (1947) 461-475.
3. Rabinowitz, J.C. and Barker, H.A. Purine fermentation by Clostridium cylindrosporum. II. Purine transformations. J. Biol. Chem. 218 (1956) 161-173.