IUBMB Enzyme Nomenclature


Accepted name: cAMP deaminase

Reaction: 3',5'-cyclic AMP + H2O = 3',5'-cyclic IMP + NH3

Other name(s): cyclic adenylate deaminase; CadD

Systematic name: 3',5'-cyclic AMP aminohydrolase

Comments: Requires Zn2+. The enzyme, isolated from the bacterium Leptospira interrogans, is specific for cAMP.

BRENDA, EXPASY, KEGG, MetaCyc, CAS registry number:


1. Goble, A.M., Feng, Y., Raushel, F.M. and Cronan, J.E. Discovery of a cAMP deaminase that quenches cyclic AMP-dependent regulation. ACS Chem. Biol. 8 (2013) 2622-2629. [PMID: 24074367]

[EC created 2017]

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