IUBMB Enzyme Nomenclature


Accepted name: bromoxynil nitrilase

Reaction: 3,5-dibromo-4-hydroxybenzonitrile + 2 H2O = 3,5-dibromo-4-hydroxy-benzoate + NH3

Systematic name: 3,5-dibromo-4-hydroxybenzonitrile aminohydrolase

Comments: Involved in the bacterial degradation of the herbicide bromoxynil. Highly specific.

Links to other databases: BRENDA, EAWAG-BBD, EXPASY, KEGG, Metacyc, CAS registry number: 157857-12-0


1. Stalker, D.M., Malyj, L.D. and McBride, K.E. Purification and properties of a nitrilase specific for the herbicide bromoxynil and corresponding nucleotide sequence analysis of the bxn gene. J. Biol. Chem. 263 (1988) 6310-6314. [PMID: 2834373]

[EC created 1992]

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