Reaction: deacetylipecoside + H2O = dopamine + secologanin
For diagram of reaction click here
Glossary: dopamine = 4-(2-aminoethyl)benzene-1,2-diol
Other name(s): deacetylipecoside dopamine-lyase; deacetylipecoside dopamine-lyase (secologanin-forming)
Systematic name: deacetylipecoside dopamine-hydroyase (secologanin-forming)
Comments: The enzyme from the leaves of Alangium lamarckii differs in enantiomeric specificity from EC 3.5.99.15, deacetylisoipecoside synthase. The product is rapidly converted to demethylalangiside.
Links to other databases: BRENDA, EXPASY, KEGG, MetaCyc, CAS registry number:
References:
1. DeEknamkul, W., Ounaroon, A., Tanahashi, T., Kutchan, T. and Zenk, M.H. Enzymatic condensation of dopamine and secologanin by cell-free extracts of Alangium lamarckii. Phytochemistry 45 (1997) 477-484.
2. De-Eknamkul, W., Suttipanta, N. and Kutchan, T.M. Purification and characterization of deacetylipecoside synthase from Alangium lamarckii Thw. Phytochemistry 55 (2000) 177-181. [PMID: 11065292]