IUBMB Enzyme Nomenclature

EC 3.6.1.57

Accepted name: UDP-2,4-diacetamido-2,4,6-trideoxy-β-L-altropyranose hydrolase

Reaction: UDP-2,4-diacetamido-2,4,6-trideoxy-β-L-altropyranose + H2O = 2,4-diacetamido-2,4,6-trideoxy-β-L-altropyranose + UDP

Glossary: pseudaminic acid = 5,7-diacetamido-3,5,7,9-tetradeoxy-L-glycero-α-L-manno-2-nonulopyranosonic acid

Other name(s): PseG; UDP-6-deoxy-AltdiNAc hydrolase; Cj1312; UDP-2,4-bis(acetamido)-2,4,6-trideoxy-β-L-altropyranose hydrolase

Systematic name: UDP-2,4-diacetamido-2,4,6-trideoxy-β-L-altropyranose hydrolase

Comments: The enzyme is involved in biosynthesis of pseudaminic acid.

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, PDB, CAS registry number:

References:

1. Liu, F. and Tanner, M.E. PseG of pseudaminic acid biosynthesis: a UDP-sugar hydrolase as a masked glycosyltransferase. J. Biol. Chem. 281 (2006) 20902-20909. [PMID: 16728396]

2. Schoenhofen, I.C., McNally, D.J., Brisson, J.R. and Logan, S.M. Elucidation of the CMP-pseudaminic acid pathway in Helicobacter pylori: synthesis from UDP-N-acetylglucosamine by a single enzymatic reaction. Glycobiology 16 (2006) 8C. [PMID: 16751642]

[EC 3.6.1.57 created 2011]


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