IUBMB Enzyme Nomenclature


Accepted name: ATP diphosphatase

Reaction: ATP + H2O = AMP + diphosphate

Other name(s): ATPase (ambiguous); ATP pyrophosphatase; adenosine triphosphate pyrophosphatase; ATP diphosphohydrolase [ambiguous]

Systematic name: ATP diphosphohydrolase (diphosphate-forming)

Comments: Also acts on ITP, GTP, CTP and UTP.

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, PDB, CAS registry number: 37289-25-1


1. Heppel, L.A. and Hilmoe, R.J. Mechanism of enzymatic hydrolysis of adenosinetriphosphate. J. Biol. Chem. 202 (1953) 217-226.

2. Johnson, M., Kaye, M.A.G., Hems, R. and Krebs, H.A. Enzymic hydrolysis of adenosine phosphates by cobra venom. Biochem. J. 54 (1953) 625-629.

[EC created 1961]

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