IUBMB Enzyme Nomenclature


Accepted name: peroxisome-assembly ATPase

Reaction: ATP + H2O = ADP + phosphate

Other name(s): peroxisome assembly factor-2

Systematic name: ATP phosphohydrolase (peroxisome-assembling)

Comments: An extremely diversified group of enzymes that use the energy of ATP hydrolysis to import and assemble peroxisome components into the organelle. Their molecular masses range from 25 to 600 kDa.

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, CAS registry number:


1. Lee, Y.J. and Wickner, R.B. AFG1, a new member of the SEC18-NSF, PAS1, CDC48-VCP, TBP family of ATPases. Yeast 8 (1992) 787-790. [PMID: 1441755]

2. Tsukamoto,T., Miura, S., Nakai, T., Yokota, S., Shimozawa, N., Suzuki, Y., Orii, T., Fujiki, Y., Sakai, F., Bogaki, A., Yasumo, H. and Osumi, T. Peroxisome assembly factor-2, a putative ATPase cloned by functional complementation on a peroxisome-deficient mammalian cell mutant. Nat. Genet. 11 (1995) 395-401. [PMID: 7493019]

3. Yahraus, T., Braverman, N., Dodt, G., Kalish, J.E., Morrell, J.C., Moser, H.W., Valle, D. and Gould, S.J. The peroxisome biogenesis disorder group 4 gene, PXAAA1, encodes a cytoplasmic ATPase required for stability of the PTS1 receptor. EMBO J. 15 (1996) 2914-2923. [PMID: 8670792]

[EC created 2000]

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