IUBMB Enzyme Nomenclature


Accepted name: cyclohexane-1,2-dione hydrolase

Reaction: cyclohexane-1,2-dione + H2O = 6-oxohexanoate

Other name(s): cyclohexane-1,2-dione acylhydrolase (decyclizing)

Systematic name: cyclohexane-1,2-dione acylhydrolase (ring-opening)

Comments: Highly specific; does not act on cyclohexanone or cyclohexane-1,3-dione as substrate.

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, PDB, CAS registry number:


1. Harder, J. Anaerobic degradation of cyclohexane-1,2-diol by a new Azoarcus species. Arch. Microbiol. 168 (1997) 199-204.

2. Fraas, S., Steinbach, A.K., Tabbert, A., Harder, J., Ermler, U., Tittmann, K., Meyer, A. and Kroneck P.M.H. Cyclohexane-1,2-dione hydrolase: A new tool to degrade alicyclic compounds. J. Mol. Catalysis B: Enzymatic 61 (2009) 47-49.

[EC created 2009]

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