IUBMB Enzyme Nomenclature


Accepted name: 2,6-dioxo-6-phenylhexa-3-enoate hydrolase

Reaction: 2,6-dioxo-6-phenylhexa-3-enoate + H2O = benzoate + 2-oxopent-4-enoate

Other name(s): HOHPDA hydrolase

Systematic name: 2,6-dioxo-6-phenylhexa-3-enoate benzoylhydrolase

Comments: Cleaves the products from biphenol, 3-isopropylcatechol and 3-methylcatechol produced by EC biphenyl-2,3-diol 1,2-dioxygenase, by ring-fission at a -CO-C bond. Involved in the breakdown of biphenyl-related compounds by Pseudomonas sp.

Links to other databases: BRENDA, EAWAG-BBD, EXPASY, KEGG, Metacyc, PDB, CAS registry number: 102925-38-2


1. Omori, T., Sugimura, K., Ishigooka, H. and Minoda, Y. Purification and some properties of a 2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoic acid hydrolyzing enzyme from Pseudomonas cruciviae S93 B1 involved in the degradation of biphenyl. Agric. Biol. Chem. 50 (1986) 931-937.

[EC created 1989]

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