IUBMB Enzyme Nomenclature


Accepted name: phosphoamidase

Reaction: N-phosphocreatine + H2O = creatine + phosphate

Other name(s): creatine phosphatase

Systematic name: phosphamide hydrolase

Comments: Also acts on N-phospho-arginine and other phosphoamides. Possibly identical with EC (glucose-6-phosphatase) or EC (protein-serine/threonine phosphatase).

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, PDB, CAS registry number: 9001-79-0


1. Parvin, R. and Smith, R.A. Phosphoramidates. V. Probable identity of rat liver microsomal glucose 6-phosphatase, phosphoramidase, and phosphoramidate-hexose phosphotransferase. Biochemistry 8 (1969) 1748. [PMID: 4308726]

2. Singer, M.F. and Fruton, J.S. Some properties of beef spleen phosphoamidase. J. Biol. Chem. 229 (1957) 111-119.

3. Sundarajan, T.A. and Sarma, P.S. Substrate specificity of phosphoprotein phosphatase from spleen. Biochem. J. 71 (1959) 537-544.

[EC created 1961]

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