IUBMB Enzyme Nomenclature


Accepted name: D-ornithine/D-lysine decarboxylase

Reaction: (1) D-ornithine = putrescine + CO2
(2) D-lysine = cadaverine + CO2

For diagram of reaction click here.

Glossary: cadaverine = pentane-1,5-diamine
putrescine = butane-1,4-diamine

Other name(s): dokD (gene name); DOKDC

Systematic name: D-ornithine/D-lysine carboxy-lyase

Comments: The enzyme, characterized from the bacterium Salmonella typhimurium LT2, is specific for D-ornithine and D-lysine. Requires pyridoxal 5'-phosphate.

Links to other databases: BRENDA, EXPASY, KEGG, MetaCyc, PDB, CAS registry number:


1. Phillips, R.S., Poteh, P., Miller, K.A. and Hoover, T.R. STM2360 encodes a D-ornithine/D-lysine decarboxylase in Salmonella enterica serovar typhimurium. Arch. Biochem. Biophys. 634 (2017) 83-87. [PMID: 29024617]

[EC created 2019]

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