Reaction: (1) D-ornithine = putrescine + CO2
(2) D-lysine = cadaverine + CO2
For diagram of reaction click here.
Glossary: cadaverine = pentane-1,5-diamine
putrescine = butane-1,4-diamine
Other name(s): dokD (gene name); DOKDC
Systematic name: D-ornithine/D-lysine carboxy-lyase
Comments: The enzyme, characterized from the bacterium Salmonella typhimurium LT2, is specific for D-ornithine and D-lysine. Requires pyridoxal 5'-phosphate.
Links to other databases: BRENDA, EXPASY, KEGG, MetaCyc, PDB, CAS registry number:
1. Phillips, R.S., Poteh, P., Miller, K.A. and Hoover, T.R. STM2360 encodes a D-ornithine/D-lysine decarboxylase in Salmonella enterica serovar typhimurium. Arch. Biochem. Biophys. 634 (2017) 83-87. [PMID: 29024617]