Reaction: L-cysteate = taurine + CO2
Other name(s): CAD
Systematic name: L-cysteate carboxy-lyase (taurine-forming)
Comments: Requires pyridoxal 5'-phosphate. The enzyme, characterized from chicken, is specific for L-cysteate and has poor activity with 3-sulfino-L-alanine. cf. EC 220.127.116.11, sulfinoalanine decarboxylase.
Links to other databases: BRENDA, EXPASY, KEGG, MetaCyc, CAS registry number:
1. Malatesta, M., Mori, G., Acquotti, D., Campanini, B., Peracchi, A., Antin, P.B. and Percudani, R. Birth of a pathway for sulfur metabolism in early amniote evolution. Nat Ecol Evol 4 (2020) 1239-1246. [PMID: 32601391]