Reaction: L-tyrosine = tyramine + CO2
For diagram of reaction click here.
Other name(s): L-tyrosine decarboxylase; L-(–)-tyrosine apodecarboxylase; L-tyrosine carboxy-lyase
Systematic name: L-tyrosine carboxy-lyase (tyramine-forming)
Comments: A pyridoxal-phosphate protein. The bacterial enzyme also acts on 3-hydroxytyrosine and, more slowly, on 3-hydroxyphenylalanine.
Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, PDB, CAS registry number: 9002-09-9
References:
1. McGilvery, R.W. and Cohen, P.P. The decarboxylation of L-phenylalanine by Streptococcus faecalis R. J. Biol. Chem. 174 (1948) 813-816.