IUBMB Enzyme Nomenclature


Accepted name: phosphopantothenoylcysteine decarboxylase

Reaction: N-[(R)-4'-phosphopantothenoyl]-L-cysteine = pantotheine 4'-phosphate + CO2

For diagram of reaction click here.

Other name(s): 4-phosphopantotheoylcysteine decarboxylase; 4-phosphopantothenoyl-L-cysteine decarboxylase; PPC-decarboxylase; N-[(R)-4'-phosphopantothenoyl]-L-cysteine carboxy-lyase

Systematic name: N-[(R)-4'-phosphopantothenoyl]-L-cysteine carboxy-lyase (pantotheine-4'-phosphate-forming)

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, PDB, CAS registry number: 9024-69-5


1. Brown, G.M. Requirement of cytidine triphosphate for the biosynthesis of phosphopantetheine. J. Am. Chem. Soc. 80 (1958) 3161 only.

2. Brown, G.M. The metabolism of pantothenic acid. J. Biol. Chem. 234 (1959) 370-378.

[EC created 1965]

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