IUBMB Enzyme Nomenclature

EC 4.1.1.53

Accepted name: phenylalanine decarboxylase

Reaction: L-phenylalanine = phenylethylamine + CO2

Other name(s): L-phenylalanine decarboxylase; aromatic L-amino acid decarboxylasee (ambiguous); L-phenylalanine carboxy-lyase

Systematic name: L-phenylalanine carboxy-lyase (phenylethylamine-forming)

Comments: A pyridoxal-phosphate protein. Also acts on tyrosine and other aromatic amino acids.

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, CAS registry number: 9075-72-3

References:

1. Lovenberg, W., Weissbach, H. and Udenfriend, S. Aromatic L-amino acid decarboxylase. J. Biol. Chem. 237 (1962) 89-93.

2. Schulz, A.R. and Oliner, L. The possible role of thyroid aromatic amino acid decarboxylase in thyroxine biosynthesis. Life Sci. 6 (1967) 873-880. [PMID: 6034195]

[EC 4.1.1.53 created 1972]


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