IUBMB Enzyme Nomenclature


Accepted name: phosphatidylserine decarboxylase

Reaction: phosphatidyl-L-serine = phosphatidylethanolamine + CO2

Other name(s): PS decarboxylase; phosphatidyl-L-serine carboxy-lyase

Systematic name: phosphatidyl-L-serine carboxy-lyase (phosphatidylethanolamine-forming)

Comments: A pyridoxal-phosphate protein. In Escherichia coli, the prosthetic group is a pyruvoyl group.

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, CAS registry number: 9054-78-8


1. Kanfer, J. and Kennedy, E.P. Metabolism and function of bacterial lipids. II. Biosynthesis of phospholipids in Escherichia coli. J. Biol. Chem. 239 (1964) 1720-1726.

2. Satre, M. and Kennedy, E.P. Identification of bound pyruvate essential for the activity of phosphatidylserine decarboxylase of Escherichia coli. J. Biol. Chem. 253 (1978) 479-483. [PMID: 338609]

[EC created 1976]

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