Reaction: 5-guanidino-2-oxopentanoate = 4-guanidinobutanal + CO2
Glossary: thiamine diphosphate
Other name(s): α-ketoarginine decarboxylase; 2-oxo-5-guanidinopentanoate carboxy-lyase
Systematic name: 5-guanidino-2-oxopentanoate carboxy-lyase (4-guanidinobutanal-forming)
Comments: enzyme activity is dependent on the presence of thiamine diphosphate and a divalent cation.
Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, CAS registry number: 56831-67-5
References:
1. Vanderbilt, A.S., Gaby, N.S., Rodwell, V.W. Intermediates and enzymes between α-ketoarginine and γ-guanidinobutyrate in the L-arginine catabolic pathway of Pseudomonas putida. J. Biol. Chem. 250 (1975) 5322-5329. [PMID: 237915]