IUBMB Enzyme Nomenclature

EC 4.1.1.75

Accepted name: 5-guanidino-2-oxopentanoate decarboxylase

Reaction: 5-guanidino-2-oxopentanoate = 4-guanidinobutanal + CO2

Glossary: thiamine diphosphate

Other name(s): α-ketoarginine decarboxylase; 2-oxo-5-guanidinopentanoate carboxy-lyase

Systematic name: 5-guanidino-2-oxopentanoate carboxy-lyase (4-guanidinobutanal-forming)

Comments: enzyme activity is dependent on the presence of thiamine diphosphate and a divalent cation.

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, CAS registry number: 56831-67-5

References:

1. Vanderbilt, A.S., Gaby, N.S., Rodwell, V.W. Intermediates and enzymes between α-ketoarginine and γ-guanidinobutyrate in the L-arginine catabolic pathway of Pseudomonas putida. J. Biol. Chem. 250 (1975) 5322-5329. [PMID: 237915]

[EC 4.1.1.75 created 1999]


Return to EC 4.1.1 home page
Return to EC 4.3 home page
Return to EC 4 home page
Return to Enzymes home page
Return to IUBMB Biochemical Nomenclature home page