IUBMB Enzyme Nomenclature


Accepted name: fucosterol-epoxide lyase

Reaction: (24R,241R)-fucosterol epoxide = desmosterol + acetaldehyde

Glossary: (24R,241R)-fucosterol epoxide = (3β,24R,28R)-24,28-epoxystigmast-5-en-3-ol

Other name(s): (24R,24'R)-fucosterol-epoxide acetaldehyde-lyase; (24R,24'R)-fucosterol-epoxide acetaldehyde-lyase (desmosterol-forming)

Systematic name: (24R,241R)-fucosterol-epoxide acetaldehyde-lyase (desmosterol-forming)

Comments: The insect enzyme is involved in the conversion of sitosterol into cholesterol.

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, CAS registry number: 99676-42-3


1. Prestwich, G.D., Angelastro, M., De Palma, A. and Perino, M.A. Fucosterol epoxide lyase of insects: synthesis of labeled substrates and development of a partition assay. Anal. Biochem. 151 (1985) 315-326. [PMID: 3913328]

[EC created 1989, modified 2013]

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