IUBMB Enzyme Nomenclature


Accepted name: deoxyribose-phosphate aldolase

Reaction: 2-deoxy-D-ribose 5-phosphate = D-glyceraldehyde 3-phosphate + acetaldehyde

For diagram of mechanism click here.

Other name(s): phosphodeoxyriboaldolase; deoxyriboaldolase; deoxyribose-5-phosphate aldolase; 2-deoxyribose-5-phosphate aldolase; 2-deoxy-D-ribose-5-phosphate acetaldehyde-lyase

Systematic name: 2-deoxy-D-ribose-5-phosphate acetaldehyde-lyase (D-glyceraldehyde-3-phosphate-forming)

Links to other databases: BRENDA, EXPASY, GTD, KEGG, Metacyc, PDB, CAS registry number: 9026-97-5


1. Hoffee, P.A. 2-Deoxyribose-5-phosphate aldolase of Salmonella typhimurium: purification and properties. Arch. Biochem. Biophys. 126 (1968) 795-802 [PMID: 4879701]

2. Jedziniak, J.A. and Lionetti, F.J. Purification and properties of deoxyriboaldolase from human erythrocytes. Biochim. Biophys. Acta 212 (1970) 478-487. [PMID: 4989681]

3. Racker, E. Enzymatic synthesis and breakdown of desoxyribose phosphate. J. Biol. Chem. 196 (1952) 347-365.

4. Hoffee, P. Rosen, O.M. and Horecker, B.L. The mechanism of action of aldolases. VI. Crystallization of deoxyribose 5-phosphate aldolase and the number of active sites. J. Biol. Chem. 240 (1965) 1512-1516.

[EC created 1961]

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