IUBMB Enzyme Nomenclature


Accepted name: citryl-CoA lyase

Reaction: (3S)-citryl-CoA = acetyl-CoA + oxaloacetate

Other name(s): (3S)-citryl-CoA oxaloacetate-lyase

Systematic name: (3S)-citryl-CoA oxaloacetate-lyase (acetyl-CoA-forming)

Comments: The enzyme is a component of EC {[citrate (pro-3S)-lyase]}and EC [ATP citrate synthase]. Also acts on (3S)-citryl thioacyl-carrier protein.

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, CAS registry number: 131095-35-7


1. Dimroth, P., Loyal, R. and Eggerer, H. Characterization of the isolated transferase subunit of citrate lyase as a CoA-transferase. Evidence against a covalent enzyme-substrate intermediate. Eur. J. Biochem. 80 (1977) 479-488. [PMID: 336371]

2. Lill, U., Schreil, A. and Eggerer, H. Isolation of enzymically active fragments formed by limited proteolysis of ATP citrate lyase. Eur. J. Biochem. 125 (1982) 645-650. [PMID: 6749502]

[EC created 1984, modified 1986]

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