Reaction: (1) 2,4',7-trihydroxyisoflavanone = daidzein + H2O
(2) 2,4',5,7-tetrahydroxyisoflavanone = genistein + H2O
For diagram of reaction click here or click here.
Glossary: daidzein = 4',7-dihydroxyisoflavone
genistein = 4',5,7-dihydroxyisoflavone
Other name(s): 2,7,4'-trihydroxyisoflavanone hydro-lyase; 2,7,4'-trihydroxyisoflavanone hydro-lyase (daidzein-forming)
Systematic name: 2,4',7-trihydroxyisoflavanone hydro-lyase (daidzein-forming)
Comments: Catalyses the final step in the formation of the isoflavonoid skeleton. The reaction also occurs spontaneously.
Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, PDB, CAS registry number: 166800-10-8
References:
1. Hakamatsuka, T., Mori, K., Ishida, S., Ebizuka, Y and Sankawa, U. Purification of 2-hydroxyisoflavanone dehydratase from the cell cultures of Pueraria lobata. Phytochemistry 49 (1998) 497-505.