IUBMB Enzyme Nomenclature


Accepted name: arabidiol synthase

Reaction: arabidiol = (3S)-2,3-epoxy-2,3-dihydrosqualene + H2O

For diagram of reaction click here.

Glossary: arabidiol = (13R)-malabarica-17,21-diene-3β,14-diol

Other name(s): PEN1 (gene name); (S)-squalene-2,3-epoxide hydro-lyase (arabidiol forming)

Systematic name: (3S)-2,3-epoxy-2,3-dihydrosqualene hydro-lyase (arabidiol forming)

Comments: The reaction occurs in the reverse direction.

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, CAS registry number:


1. Xiang, T., Shibuya, M., Katsube, Y., Tsutsumi, T., Otsuka, M., Zhang, H., Masuda, K. and Ebizuka, Y. A new triterpene synthase from Arabidopsis thaliana produces a tricyclic triterpene with two hydroxyl groups. Org Lett 8 (2006) 2835-2838. [PMID: 16774269]

[EC created 2011]

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