IUBMB Enzyme Nomenclature


Accepted name: sporulenol synthase

Reaction: sporulenol = tetraprenyl-β-curcumene + H2O

For diagram of reaction click here.

Glossary: sporulenol = (1R,2R,4aS,4bR,6aS,10aS,10bR,12aS)-2,4b,7,7,10a,12a-hexamethyl-1-[(3R)-3-(4-methylcyclohexa-1,4-dien-1-yl)butyl]octadecahydrochrysen-2-ol

Other name(s): sqhC (gene name)

Systematic name: tetraprenyl-β-curcumene—sporulenol cyclase

Comments: The reaction occurs in the reverse direction. Isolated from Bacillus subtilis. Similar sesquarterpenoids are present in a number of Bacillus species.

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, CAS registry number:


1. Sato, T., Yoshida, S., Hoshino, H., Tanno, M., Nakajima, M. and Hoshino, T. Sesquarterpenes (C35 terpenes) biosynthesized via the cyclization of a linear C35 isoprenoid by a tetraprenyl-β-curcumene synthase and a tetraprenyl-β-curcumene cyclase: identification of a new terpene cyclase. J. Am. Chem. Soc. 133 (2011) 9734-9737. [PMID: 21627333]

[EC created 2012]

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