IUBMB Enzyme Nomenclature

EC 4.2.1.146

Accepted name: L-galactonate dehydratase

Reaction: L-galactonate = 2-dehydro-3-deoxy-L-galactonate + H2O

Other name(s): LGD1

Systematic name: L-galactonate hydro-lyase (2-dehydro-3-deoxy-L-galactonate-forming)

Comments: The enzyme takes part in a D-galacturonate degradation pathway in the fungi Trichoderma reesei (Hypocrea jecorina) and Aspergillus niger.

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, CAS registry number:

References:

1. Kuorelahti, S., Jouhten, P., Maaheimo, H., Penttila, M. and Richard, P. L-Galactonate dehydratase is part of the fungal path for D-galacturonic acid catabolism. Mol. Microbiol. 61 (2006) 1060-1068. [PMID: 16879654]

2. Martens-Uzunova, E.S. and Schaap, P.J. An evolutionary conserved D-galacturonic acid metabolic pathway operates across filamentous fungi capable of pectin degradation. Fungal Genet. Biol. 45 (2008) 1449-1457. [PMID: 18768163]

[EC 4.2.1.146 created 2013]


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