IUBMB Enzyme Nomenclature


Accepted name: cis-L-3-hydroxyproline dehydratase

Reaction: cis-3-hydroxy-L-proline = 1-pyrroline-2-carboxylate + H2O

Glossary: 1-pyrroline-2-carboxylate = 4,5-dihydro-3H-pyrrole-2-carboxylate

Other name(s): cis-L-3-hydroxyproline hydro-lyase; c3LHypD

Systematic name: cis-3-hydroxy-L-proline hydro-lyase (1-pyrroline-2-carboxylate-forming)

Links to other databases: BRENDA, EXPASY, KEGG, MetaCyc, CAS registry number:


1. Zhang, X., Kumar, R., Vetting, M.W., Zhao, S., Jacobson, M.P., Almo, S.C. and Gerlt, J.A. A unique cis-3-hydroxy-L-proline dehydratase in the enolase superfamily. J. Am. Chem. Soc. 137 (2015) 1388-1391. [PMID: 25608448]

[EC created 2017]

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