IUBMB Enzyme Nomenclature


Accepted name: ent-8α-hydroxylabd-13-en-15-yl diphosphate synthase

Reaction: ent-8α-hydroxylabd-13-en-15-yl diphosphate = geranylgeranyl diphosphate + H2O

For diagram of reaction click here

Other name(s): SmCPS4

Systematic name: geranylgeranyl-diphosphate hydro-lyase (ent-8α-hydroxylabd-13-en-15-yl diphosphate forming)

Comments: Isolated from the plant Salvia miltiorrhiza (red sage).

Links to other databases: BRENDA, EXPASY, KEGG, MetaCyc, CAS registry number:


1. Cui, G., Duan, L., Jin, B., Qian, J., Xue, Z., Shen, G., Snyder, J.H., Song, J., Chen, S., Huang, L., Peters, R.J. and Qi, X. Functional divergence of diterpene syntheses in the medicinal plant Salvia miltiorrhiza. Plant Physiol. 169 (2015) 1607-1618. [PMID: 26077765]

[EC created 2017]

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