IUBMB Enzyme Nomenclature

EC 4.2.1.176

Accepted name: L-lyxonate dehydratase

Reaction: L-lyxonate = 2-dehydro-3-deoxy-L-arabinonate + H2O

Glossary: L-lyxonate = (2R,3R,4S)-2,3,4,5-tetrahydroxypentanoate

Other name(s): lyxD (gene name)

Systematic name: L-lyxonate hydro-lyase

Comments: The enzyme, characterized from several bacterial species, is involved in an L-lyxonate degradation pathway.

Links to other databases: BRENDA, EXPASY, KEGG, MetaCyc, CAS registry number:

References:

1. Ghasempur, S., Eswaramoorthy, S., Hillerich, B.S., Seidel, R.D., Swaminathan, S., Almo, S.C. and Gerlt, J.A. Discovery of a novel L-lyxonate degradation pathway in Pseudomonas aeruginosa PAO1. Biochemistry 53 (2014) 3357-3366. [PMID: 24831290]

[EC 4.2.1.176 created 2021]


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