IUBMB Enzyme Nomenclature


Accepted name: (R)-2-methylmalate dehydratase

Reaction: (R)-2-methylmalate = 2-methylmaleate + H2O

Other name(s): citraconate hydratase; citraconase; citramalate hydro-lyase; (–)-citramalate hydro-lyase; (R)-2-methylmalate hydro-lyase

Systematic name: (R)-2-methylmalate hydro-lyase (2-methylmaleate-forming)

Comments: Requires Fe2+.

Links to other databases: BRENDA, EXPASY, GTD, KEGG, Metacyc, PDB, CAS registry number: 9027-92-3


1. Subramanian, S.S. and Raghavendra Rao, M.R. Purification and properties of citraconase. J. Biol. Chem. 243 (1968) 2367-2372. [PMID: 4296839]

2. Raghavendra Rao, M.R., Subramanian, S.S., Rahatekar, H.I. and Paranjape, S.V. Enzymatic hydration of citraconate to (–)citramalate. Biochem. Biophys. Res. Commun. 12 (1963) 78-82. [PMID: 13973053]

[EC created 1972]

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