Reaction: D-galactonate = 2-dehydro-3-deoxy-D-galactonate + H2O
For diagram of reaction click here.
Other name(s): D-galactonate dehydrase; D-galactonate dehydratase; D-galactonate hydro-lyase
Systematic name: D-galactonate hydro-lyase(2-dehydro-3-deoxy-D-galactonate-forming)
Comments: The enzyme shows no activity with D-gluconate [2]. cf. EC 4.2.1.140, gluconate/galactonate dehydratase.
Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, PDB, CAS registry number: 9024-38-8
References:
1. De Ley, J. and Doudoroff, M. The metabolism of D-galactose in Pseudomonas saccarophila. J. Biol. Chem. 227 (1957) 745-757. [PMID: 13462997]
2. Donald, A., Sibley, D., Lyons, D.E. and Dahms, A.S. D-Galactonate dehydrase. Purification and properties. J. Biol. Chem. 254 (1979) 2132-2137. [PMID: 422572]