Reaction: 16α-hydroxyprogesterone = 16,17-didehydroprogesterone + H2O
For diagram click here.
Other name(s): hydroxyprogesterone dehydroxylase; 16α-hydroxyprogesterone dehydroxylase; 16α-dehydroxylase; 16α-hydroxyprogesterone hydro-lyase
Systematic name: 16α-hydroxyprogesterone hydro-lyase (16,17-didehydroprogesterone-forming)
Comments: 16α-Hydroxypregnenolone is also a substrate.
Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, CAS registry number: 89287-36-5
1. Glass, T.L. and Lamppa, R.S. Purification and properties of 16α-hydroxyprogesterone dehydroxylase from Eubacterium sp. strain 144. Biochim. Biophys. Acta 837 (1985) 103-110. [PMID: 4052439]