Reaction: an α-L-rhamnose-(1→4)-β-D-glucuronide = α-L-rhamnopyranose + a 4-deoxy-α-L-threo-hex-4-enopyranuronoside
Other name(s): L-rhamnose-α-1,4-D-glucuronate lyase; FoRham (gene name)
Systematic name: α-L-rhamnosyl-(1→4)-β-D-glucuronate lyase
Comments: The enzyme, characterized from the phytopathogenic fungus Fusarium oxysporum, removes the rhamnosyl residue from α-L-rhamnosyl-(1→4)-β-D-glucuronate or from oligosaccharides that contain this motif at the non-reducing end, leaving an unsaturated glucuronate residue. Among its natural substrates is the type II arabinogalactan component of gum arabic.
1. Kondo, T., Kichijo, M., Maruta, A., Nakaya, M., Takenaka, S., Arakawa, T., Fushinobu, S. and Sakamoto, T. Structural and functional analysis of gum arabic L-rhamnose-α-1,4-D-glucuronate lyase establishes a novel polysaccharide lyase family. J. Biol. Chem. 297 (2021) 101001. [PMID: 34303708]