Reaction: (2E,6E)-farnesyl diphosphate = bicyclogermacrene + diphosphate
For diagram of reaction click here.
Other name(s): Ov-TPS4
Systematic name: (2E,6E)-farnesyl-diphosphate diphosphate-lyase (bicyclogermacrene-forming)
Comments: The enzyme from oregano (Origanum vulgare) gives mainly bicyclogermacrene with Mn2+ as a cofactor. With Mg2+ a more complex mixture is produced.
Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, CAS registry number:
1. Crocoll, C., Asbach, J., Novak, J., Gershenzon, J. and Degenhardt, J. Terpene synthases of oregano (Origanum vulgare L.) and their roles in the pathway and regulation of terpene biosynthesis. Plant Mol. Biol. 73 (2010) 587-603. [PMID: 20419468]