IUBMB Enzyme Nomenclature


Accepted name: (–)-sabinene synthase

Reaction: geranyl diphosphate = (–)-sabinene + diphosphate

For diagram of reaction click here.

Glossary: (–)-sabinene = (1S,5S)-1-isopropyl-4-methylenebicyclo[3.1.0]hexane

Systematic name: geranyl-diphosphate diphosphate-lyase [cyclizing, (–)-sabinene-forming]

Comments: Requires Mg2+. Isolated from Pinus contorta (lodgepole pine) as cyclase I [1] and from Conocephalum conicum (liverwort) [2].

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, CAS registry number:


1. Savage, T.J., Hatch, M.W. and Croteau, R. Monoterpene synthases of Pinus contorta and related conifers. A new class of terpenoid cyclase. J. Biol. Chem. 269 (1994) 4012-4020. [PMID: 8307957]

2. Peters, R.J. and Croteau, R.B. Alternative termination chemistries utilized by monoterpene cyclases: chimeric analysis of bornyl diphosphate, 1,8-cineole, and sabinene synthases. Arch. Biochem. Biophys. 417 (2003) 203-211. [PMID: 12941302]

[EC created 2012]

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