Reaction: geranyl diphosphate = (+)-β-pinene + diphosphate
For diagram of reaction click here.
Glossary: (+)-β-pinene = (1R,5R)-6,6-dimethyl-2-methylenebicyclo[3.1.1]hept-2-ene
Other name(s): (+)-pinene cyclase; cyclase III
Systematic name: geranyl-diphosphate diphosphate-lyase [(+)-β-pinene-forming]
Comments: Cyclase III from Salvia officinalis (sage) gives roughly equal parts of (+)-β-pinene and (+)-α-pinene. See EC 4.2.3.121, (+)-α-pinene synthase.
Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, CAS registry number:
References:
1. Wagschal, K.C., Pyun, H.J., Coates, R.M. and Croteau, R. Monoterpene biosynthesis: isotope effects associated with bicyclic olefin formation catalyzed by pinene synthases from sage (Salvia officinalis). Arch. Biochem. Biophys. 308 (1994) 477-487. [PMID: 8109978]
2. Pyun, H.J., Wagschal, K.C., Jung, D.I., Coates, R.M. and Croteau, R. Stereochemistry of the proton elimination in the formation of (+)- and (–)-α-pinene by monoterpene cyclases from sage (Salvia officinalis). Arch. Biochem. Biophys. 308 (1994) 488-496. [PMID: 8109979]