IUBMB Enzyme Nomenclature


Accepted name: 7-epizingiberene synthase [(2Z,6Z)-farnesyl diphosphate cyclizing]

Reaction: (2Z,6Z)-farnesyl diphosphate = 7-epizingiberene + diphosphate

For diagram of reaction click here.

Glossary: 7-epizingiberene = (5R)-2-methyl-5-[(2R)-6-methylhept-5-en-2-yl]cyclohexa-1,3-diene

Other name(s): ShZIS (gene name)

Systematic name: (2Z,6Z)-farnesyl-diphosphate lyase (cyclizing; 7-epizingiberene-forming)

Comments: Isolated from the plant Solanum habrochaites. 7-Epizingiberene is a whitefly repellant.

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, CAS registry number:


1. Bleeker, P.M., Mirabella, R., Diergaarde, P.J., Vandoorn, A., Tissier, A., Kant, M.R., Prins, M., de Vos, M., Haring, M.A. and Schuurink, R.C. Improved herbivore resistance in cultivated tomato with the sesquiterpene biosynthetic pathway from a wild relative. Proc. Natl. Acad. Sci. USA 109 (2012) 20124-20129. [PMID: 23169639]

[EC created 2013]

Return to EC 4.2.3 home page
Return to EC 4.2 home page
Return to EC 4 home page
Return to Enzymes home page
Return to IUBMB Biochemical Nomenclature home page