IUBMB Enzyme Nomenclature


Accepted name: guaia-4,6-diene synthase

Reaction: (2E,6E)-farnesyl diphosphate = guaia-4,6-diene + diphosphate

For diagram of reaction click here

Other name(s): XsTPS2

Systematic name: (2E,6E)-farnesyl-diphosphate diphosphate-lyase (cyclizing, guaia-4,6-diene-forming)

Comments: Isolated from the plant Xanthium strumarium (rough cocklebur).

Links to other databases: BRENDA, EXPASY, KEGG, MetaCyc, CAS registry number:


1. Li, Y., Chen, F., Li, Z., Li, C. and Zhang, Y. Identification and functional characterization of sesquiterpene synthases from Xanthium strumarium. Plant Cell Physiol 57 (2016) 630-641. [PMID: 26858282]

[EC created 2017]

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