IUBMB Enzyme Nomenclature


Accepted name: (12E)-labda-8(17),12,14-triene synthase

Reaction: (+)-copalyl diphosphate = (12E)-labda-8(17),12,14-triene + diphosphate

For diagram of reaction click here

Other name(s): CldD

Systematic name: (+)-copalyl-diphosphate diphosphate-lyase [(12E)-labda-8(17),12,14-triene-forming]

Comments: Isolated from the bacterium Streptomyces cyslabdanicus.

Links to other databases: BRENDA, EXPASY, KEGG, MetaCyc, CAS registry number:


1. Yamada, Y., Komatsu, M. and Ikeda, H. Chemical diversity of labdane-type bicyclic diterpene biosynthesis in Actinomycetales microorganisms. J. Antibiot. (Tokyo) 69 (2016) 515-523. [PMID: 26814669]

[EC created 2017]

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