IUBMB Enzyme Nomenclature


Accepted name: eudesmane-5,11-diol synthase

Reaction: (2E,6E)-farnesyl diphosphate + 2 H2O = 7-epi-ent-eudesmane-5,11-diol + diphosphate

For diagram of reaction click here and mechanism click here.

Glossary: 7-epi-ent-eudesmane-5,11-diol = (4S,4aS,6R,8aS)-6-(2-hydroxypropan-2-yl)-4,8a-dimethyldecahydronaphthalen-4a-ol

Other name(s): ZmEDS (gene name)

Systematic name: (2E,6E)-farnesyl-diphosphate diphosphate-lyase (cyclizing, 7-epi-ent-eudesmane-5,11-diol-forming)

Comments: Isolated from the plant Zea mays (maize). The product is named in the reference using a different numbering scheme for eudesmane.

Links to other databases: BRENDA, EXPASY, KEGG, MetaCyc, CAS registry number:


1. Liang, J., Liu, J., Brown, R., Jia, M., Zhou, K., Peters, R.J. and Wang, Q. Direct production of dihydroxylated sesquiterpenoids by a maize terpene synthase. Plant J. 94 (2018) 847-856. [PMID: 29570233]

[EC created 2018]

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