IUBMB Enzyme Nomenclature


Accepted name: (–)-5-epieremophilene synthase

Reaction: (2E,6E)-farnesyl diphosphate = (–)-5-epieremophilene + diphosphate

For diagram of reaction click here

Glossary: (–)-5-epieremophilene = (3R,4aS,5S)-4a,5-dimethyl-3-(prop-1-en-2-yl)-1,2,3,4,4a,5,6,7-octahydronaphthalene

Other name(s): STPS1 (gene name); STP2 (gene name); STP3 (gene name)

Systematic name: (2E,6E)-farnesyl-diphosphate diphosphate-lyase [cyclizing, (–)-epieremophilene-forming]

Comments: The plant Salvia miltiorrhiza (danshen) produces three different forms of the enzyme, encoded by paralogous genes, that exhibit different spacial expression patterns and respond differently to hormone treatment.

Links to other databases: BRENDA, EXPASY, KEGG, MetaCyc, CAS registry number:


1. Fang, X., Li, C.Y., Yang, Y., Cui, M.Y., Chen, X.Y. and Yang, L. Identification of a novel (-)-5-epieremophilene synthase from Salvia miltiorrhiza via transcriptome mining. Front. Plant Sci. 8 (2017) 627. [PMID: 28487717]

[EC created 2018]

Return to EC 4.2.3 home page
Return to EC 4.2 home page
Return to EC 4 home page
Return to Enzymes home page
Return to IUBMB Biochemical Nomenclature home page