IUBMB Enzyme Nomenclature


Accepted name: verrucosan-2β-ol synthase

Reaction: geranylgeranyl diphosphate + H2O = verrucosan-2β-ol + diphosphate

Diagram of reaction click here

Glossary: verrucosan-2β-ol = (1S,3aR,5aS,6aR,7aR,8S,8aR,9bR)-1-(propan-2-yl)tetradecahydrocyclopenta[a]cyclopropa[g]naphthalene-8-ol

Other name(s): ChlTC2

Systematic name: geranylgeranyl-diphosphate diphosphate-lyase (verrucosan-2β-ol-forming)

Comments: Requires Mg2+. Characterized from the bacterium Chloroflexus aurantiacus.

Links to other databases: BRENDA, EXPASY, KEGG, MetaCyc, CAS registry number:


1. Yang, Y.L., Zhang, S., Ma, K., Xu, Y., Tao, Q., Chen, Y., Chen, J., Guo, S., Ren, J., Wang, W., Tao, Y., Yin, W.B. and Liu, H. Discovery and characterization of a new family of diterpene cyclases in bacteria and fungi. Angew. Chem. Int. Ed. Engl. 56 (2017) 4749-4752. [PMID: 28371074]

[EC created 2022]

Return to EC 4.2.3 home page
Return to EC 4.2 home page
Return to EC 4 home page
Return to Enzymes home page
Return to IUBMB Biochemical Nomenclature home page