Reaction: geranylgeranyl diphosphate = lydicene + diphosphate
Diagram of reaction click here
Glossary: lydicene = (4aR,6aS)-2,2,4α,6α,9-pentamethyl-2,3,4,5,6,7,10,11-octahydro-1Hcyclohepta[a]naphthalene
Other name(s): StlTC
Systematic name: geranylgerany-diphosphate diphosphate-lyase (lydicene-forming)
Comments: Requires Mg2+. Characterized from the bacterium Streptomyces lydicus.
Links to other databases: BRENDA, EXPASY, KEGG, MetaCyc, CAS registry number:
References:
1. Yang, Y.L., Zhang, S., Ma, K., Xu, Y., Tao, Q., Chen, Y., Chen, J., Guo, S., Ren, J., Wang, W., Tao, Y., Yin, W.B. and Liu, H. Discovery and characterization of a new family of diterpene cyclases in bacteria and fungi. Angew. Chem. Int. Ed. Engl. 56 (2017) 4749-4752. [PMID: 28371074]