Reaction: geranylgeranyl diphosphate = δ-araneosene + diphosphate
For diagram of reaction click here and mechanism click here
Glossary: δ-araneosene = (3aR,5E,9E)-3a,6,10-trimethyl-1-(propan-2-yl)-2,3,3a,4,7,8,11,12-octahydrocyclopenta[11]annulene
Systematic name: geranylgeranyl-diphosphate diphosphate-lyase [cyclizing, δ-araneosene-forming]
Comments: Isolated from the fungus Colletotrichum gloeosporioidea. δ-Araneosene may be involved in the biosynthesis of dolasta-1(15),8-diene (see EC 4.2.3.214, dolasta-1(15),8-diene synthase) and cycloaraneosene (see EC 4.2.3.191, cycloaraneosene synthase).
Links to other databases: BRENDA, EXPASY, KEGG, MetaCyc, CAS registry number:
References:
1. Bian, G., Rinkel, J., Wang, Z., Lauterbach, L., Hou, A., Yuan, Y., Deng, Z., Liu, T. and Dickschat, J.S. A clade II-D fungal chimeric diterpene synthase from Colletotrichum gloeosporioides produces dolasta-1(15),8-diene. Angew. Chem. Int. Ed. Engl. 57 (2018) 15887-15890. [PMID: 30277637]