IUBMB Enzyme Nomenclature


Accepted name: stemod-13(17)-ene synthase

Reaction: 9α-copalyl diphosphate = stemod-13(17)-ene + diphosphate

For diagram of reaction, click here

Glossary: syn-copalyl diphosphate = 9α-copalyl diphosphate
exo-stemodene = stemod-13(17)-ene

Other name(s): OsKSL11; stemodene synthase

Systematic name: 9α-copalyl-diphosphate diphosphate-lyase [stemod-13(17)-ene-forming]

Comments: This enzyme catalyses the committed step in the biosynthesis of the stemodane family of diterpenoid secondary metabolites, some of which possess mild antiviral activity. The enzyme also produces stemod-12-ene and stemar-13-ene as minor products.

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, CAS registry number:


1. Morrone, D., Jin, Y., Xu, M., Choi, S.Y., Coates, R.M. and Peters, R.J. An unexpected diterpene cyclase from rice: functional identification of a stemodene synthase. Arch. Biochem. Biophys. 448 (2006) 133-140. [PMID: 16256063]

[EC created 2008]

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